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doi: 10.1210/edrv-16-1-3 [DOI] [PubMed] [Google Scholar] 12

290 V-9302, an inhibitor of Gln transporter SLC1A5, increases intracellular ROS and autophagosome production

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However, overexpression of PGC-1 reduces autophagy marker levels, improves mitochondrial metabolic function and antioxidant capacity, thereby alleviating muscle atrophy, offering a potential approach to age-related sarcopenia (80)

Extensive evidence has been obtained that class III peroxidases are one of the mechanisms for launching oxidative defense in plants, but no oxidant for these enzymes has been identified in any plant parasite systems