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Pathogenic forms of syn are propagate to the central nervous system (CNS) via retrograde transport along the vagus nerve, supporting mechanistic support for the gutbrain axis hypothesis in PD [21, 23, 27]
doi: 10.1038/s41588-018-0099-7 42
[DOI] [PubMed] [Google Scholar] 67.Li G.L., Ye Y., Kang J.J., Yao X.Y., Zhang Y.Z., Jiang W., Gao M., Dai Y.D., Xin Y.Q., Wang Q., et al
Thus, energy deficiency, depleted levels of energy substrates, and glutathione depletion are widespread systemic features of AKI
