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Given the reliance of HCV on host lipid metabolism and clinical challenges posed by HCV-G3 infection, a detailed understanding of lipid perturbation in comparison with HCV-G1 may be relevant for understanding natural history of liver disease progression

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Next, dimensionality reduction and derivation of variable importance in projection (VIP) values were performed through orthogonal partial least squares-discriminant analysis (OPLSDA) implemented with the R package Ropls