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GLS1 is more ubiquitously expressed, while GLS2 is expressed mainly in the brain, liver, and pancreas

Their findings indicated that, compared with the healthy controls, there were significant reductions in hypoxanthine serum levels in ME/CFS patients during PEM, a hallmark symptom triggered by physical activity

Gastroenterology 2013;145:574-82 e1

A steady-state plasma concentration of 10 g/mL is desired
