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TIGAR plays neuroprotective roles in KA-induced excitotoxicity through reducing neuroinflammation and improving mitochondrial function

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Most studies demonstrated reductions in oxidative stress markers following curcumin-piperine treatment, including decreases in reactive oxygen species, malondialdehyde, nitrite levels, and protein carbonyl formation, alongside increases in endogenous antioxidant defenses such as glutathione, superoxide dismutase, catalase, and glutathione peroxidase

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