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Metallothionein Metallothionein, a cysteine-rich protein with the ability to bind divalent cations, including toxic metals such as mercury, cadmium, lead, and arsenic, is gaining recognition as an important component in heavy metal detoxification [190192]
This regulation led to altered expression of key autophagy-related proteins (upregulated LC3/Beclin-1, downregulated p62) and apoptosis-related proteins (increased Bcl-2/Bax ratio, reduced Caspase-3/7 levels) (130)
Barriers and Opportunities for Gemcitabine in Pancreatic Cancer Therapy
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