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The soluble fraction was separated from debris by spinning down at 20,000 g for 20 min

Yes, with proper medical supervision

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Model 2 was additionally adjusted for smoking status (never, ever, or current), physical activity (inactive, moderate, or vigorous), body mass index ( 216 nmol/L) (Table 1)

Although these results do not indicate a significant interaction between ketorolac tromethamine and warfarin or heparin, the administration of ketorolac tromethamine to patients taking anticoagulants should be done extremely cautiously, and patients should be closely monitored (see WARNINGS and PRECAUTIONS - Hematological Effects)