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J Clin Invest 2024;134(20)
Vindoline and catharanthine are two of the precursor alkaloids that are found in plants (in the waxy coating of the leaves)
IL-1 has been shown to directly induce catabolism in C2C12 derived myotubes, suggesting a direct causal relationship in cachexia [23]
10.4049/jimmunol.1801382 157
Optimal strategies require patient stratification by genetic context, tumor stage, metabolic status, and autophagy activity
