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Iron overloadinduced neuroinflammation and ferroptosis play a central role in the pathogenesis of depression by disrupting antioxidant defenses, impairing BDNF signaling, and triggering neuronal degeneration

It also directly stimulates growth hormone releasing hormonefrom the pituitary, at least in vitro

The formation of pentafluorobenzyl esters can limit fragmentation and greatly enhance sensitivity

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