cicplatin and glutathione A structure-based mechanism of cisplatin resistance mediated by transferase P1-1 Dose-dependent effect of cisplatin on

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cerevisiae, which has one of the lowest protein cysteine contents among eukaryotes, more than 5% of its total cysteines are arranged in CXXC motifs, and more than 21% of cysteines are arranged in this pattern in archaea [32]

So kann das Glutathion den Verdauungstrakt umgehen und sich direkt mit den Zellmembranen verbinden, um in die Zellen zu gelangen