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It may indicate the increased SELENOP transport across the neural barriers, due to high expression of LRP8 at the BBB, which keeps Se levels relatively stable, even during deficiency periods making an adequate Se pool available in the CNS (Zachara et al., 2001)

MOR202, a novel anti-CD38 monoclonal antibody, in patients with relapsed or refractory multiple myeloma: a first-in-human, multicentre, phase 12a trial

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Given the mechanism of enzyme inhibition, our non-covalent inhibitors can be targeted to TrxR and can be applicable to development of therapeutics for a broad range of diseases

Journal of the neurological sciences, 233(1), 93-97