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[20] Patients should contact their GP or bariatric team promptly if they experience any of the following: New or worsening tingling, numbness, or weakness in the limbs Difficulty with balance, coordination, or memory Unexplained fatigue, breathlessness, or palpitations A sore or swollen tongue, or persistent mouth ulcers Any concern that they have missed supplementation for a prolonged period Symptoms that suggest anaemia, such as pallor or dizziness New or worsening neurological symptoms such as paraesthesia, gait disturbance, or cognitive change warrant same-day assessment

This metabolite is part of the brains ReninAngiotensin System (RAS)

As we age, stomach acid production can decline (atrophic gastritis), which makes it harder to extract B12 from food or pills

Could older adults with impaired absorption respond differently

Camille Kotton, an infectious diseases doctor at Massachusetts General Hospital