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Regional mitochondrial heterogeneity dictates ischemic vulnerability: Gray matter, with 50% higher mitochondrial density (MitoD) than white matter, exhibits heightened susceptibility to energy failure during ischemia [49] (Box 1)

The National Academies Press

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Kevin Klatt, PhD, RD, an assistant research scientist and instructor in the Department of Nutrition Sciences and Toxicology at University of California, Berkeley, cautions that epidemiological studies using circulating levels of nutrients or metabolites as proxies for dietary exposure often dont correlate with randomized controlled trials that aim to increase levels of those nutrients or metabolites

The authors emphasise the need for education, improved access to comprehensive information, and support from the healthcare team for patients diagnosed with type 1 diabetes in the context of low-carbohydrate diets [186]