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doi: 10.1158/1055-9965.EPI-13-1057 5 WangJPSunYHBertagnolliMM

The tail vein injection represents the most widely used systemic approach, offering advantages such as ease of operation and feasibility for repeated dosing

Arch Intern Med 140(11):14731475 Ruginsk SG, Lopes da Silva A, Ventura RR, Elias LLK, Antunes-Rodrigues J (2009) Central actions of glucocorticoids in the control of body fluid homeostasis: review
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Dexmedetomidine Provides Cardioprotection During Early or Late Reperfusion Mediated by Different Mitochondrial K+-Channels

Treatment response depends on deficiency severity, route of administration, underlying cause, patient age, concurrent medical conditions, and medication interactions