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1 Introduction Sepsis-associated encephalopathy (SAE) represents a severe complication of sepsis, defined by diffuse brain dysfunction without direct central nervous system (CNS) infection ( Oxidative stress is central to SAE pathogenesis, driven by an imbalance between excessive reactive oxygen species (ROS) production and impaired antioxidant defense systems ( The antioxidant defense system, especially GSH metabolism, is linked to neurodegenerative diseases ( Proteomics and metabolomics enable systematic profiling of protein expression and metabolic signatures

Lactobacillus gasseri LGV03 isolated from the cervico-vagina of HPV-cleared women modulates epithelial innate immune responses and suppresses the growth of HPV-positive human cervical cancer cells

Multiple Sclerosis Multiple sclerosis (MS) is a chronic neurodegenerative disease of the central nervous system characterized by a combination of inflammation, demyelination, and axonal damage, with an unpredictable course of disease progression, which is associated with high oxidative stress

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The phenotypic manifestations of ASD are largely heterogeneous, which might be explained by complex interaction of genetic susceptibility with different risk factors, leading to an individual path of developing ASD in each person