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doi: 10.1038/nrm1960 57 AkabasMH

USA 108 , 13971402 (2011)
Some of the key roles of B12 in your body include: Helping in the normal functioning of the nervous system Playing a vital role in DNA synthesis B12 is among the vitamins needed in the breakdown of amino acids and fatty acids Helps in the creation and maturation of red blood cells (hemoglobin) in the bone marrow Supports the production of digestive enzymes and the delivery of essential nutrients to and from cells Its vital to the development of a fetus in pregnant women Having a deficiency in vitamin B12 can lead to several different symptoms, including fatigue, headaches, pale skin, anemia, vision issues, sores of the mouth/tongue, and even cognitive functioning changes

In the case of the subject that dropped out of the study, the pre-treatment laboratory work shows a baseline depletion of the glutathione reserve, high levels of superoxide dismutase despite normal glutathione peroxidase, and elevated lipid peroxides
