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Figure 4 Fer-1 activates the Nrf2 antioxidant system, leading to elevated GPX4 levels and increased type II collagen production in chondrocytes

Each component represents a distinct structural class of peptide.nnGHK-Cu is a copper-bound tripeptide first isolated from human plasma in 1973.nnBPC-157 is a synthetic 15-amino-acid peptide derived from a partial sequence of a protein found in human gastric juice.nnTB-500 is a synthetic peptide based on the Thymosin Beta-4 sequence, a 43-amino-acid polypeptide naturally expressed in many human tissues.nnGLOW is studied in preclinical experiments examining collagen synthesis, extracellular matrix remodelling, angiogenic activity, and tissue-repair processes, with each peptide contributing to a different stage of the regenerative cycle

Journal of Agricultural and Food Chemistry

The GSH-cognition relationship with opposite patterns in both age groups suggests that GSH levels (in IPL) may be indicative of different underlying processes in young and older adults