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On the other hand, statistically significant increases were observed in L-carnitine treated medakas in spermidine levels (ratio: 1.3), -aminobutyric acid (GABA) (ratio: 1.6), allantoic acid (ratio: 2.0), and dihydroxyacetone phosphate (ratio: 1.5), while 2-aminoadipic acid (ratio: 0.7), 3-methylhistidine (ratio: 0.6), -Glu-Cys (ratio: 0.7), and 5-oxoproline (ratio: 0.7) decreased (Table 1)

Then, the results will be evaluated by the trial steering committee

ANTI-PUFFINESS AND ANTI-DARK CIRCLE ACTION The combination of plant-based expert key ingredients, including Atlas Cedar extract and Pomegranate fermented extract, helps to lighten the blue and brown coloration of dark circles: the eyes look visibly brighter

Moreover, the neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation associated with subclinical atherosclerosis [33], during and after the supplementation remained at a level 1.8, which was comparable to the control subjects [34]