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doi:10.1152/ajpgi.1990.259.4

The IC 50 values for the ripe fruit pulp, ripe fruit seeds, unripe fruit pulp, and unripe fruit seeds were 27.78, 89.1, 77.33, and 75.2 g/mL for HepG2 cells, respectively

McDonald, D

Gene expression modulation studies (over 4,000 human genes documented)

About 15% of people don't respond to medication at all, or the side effects outweigh the benefits, but if it works then it works
