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In addition, non-specific agents can produce toxic side effects that reduce adherence [47, 67, 92]
247 Ospemifene does not stimulate the endometrium, but may worsen hot flashes and increase blood clot risk

This phenomenon is dependent on the ratio of antibody to antigen and tends to occur in conditions of antigen excess ( There are several examples of approved therapeutics with potentially immune complex-mediated immunogenicity

80% of rectal cancers can be detected, but a negative digital examination does not completely rule out rectal cancer

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