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Lephart ED, Naftolin F

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

doi: 10.1177/11795514241249013

Injection of A42 into rat basal forebrain followed a week later by examination of oxidative damage in hippocampus demonstrated a significant elevated level of HNE-modified proteins (13), consistent with the known diffusion of HNE from its site of origin in cell or organelle membranes to other areas within the cell (8, 34) and consistent with the connection between the forebrain and outer molecular layer of hippocampus (98)

This finding is quite contradictory to the belief that acetaldehyde plays a role in liver damage