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Moreover, leptin treatment led to changes in endocrine and metabolic parameters such as thyroid hormones and total lipids or triacylglycerol concentrations during post-hatch development (194)

Also, region-specific intraneuronal iron load was assessed by T2* MRI and was shown to decrease in the active-treatment groups, but it did not correlate with significant clinical improvement in terms of changes in the UPDRS scores (Martin-Bastida et al

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Yet, we find NE SCLC to also depend on anti-oxidant defense via the TRX pathway suggesting elevated ROS to also be a problem in this subtype