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Metabolic rate and energy expenditure: While AOD9604 mainly works through direct effects on fat cells, some research suggests it may also modestly increase metabolic rate and energy expenditure

Summary While adipocyte DNL contributes to lipid storage, lipid precursors may have additional second messenger functions critical for maintaining adipocyte health, and thus systemic metabolic homeostasis

Clinically used small molecule drugs of ROCK signaling Netarsudil (N) and Wnt signaling LY2090314 (L) were also tested

Absorption and Retention With Injections Both forms bypass the digestive system when given as intramuscular injections, making absorption rates nearly identical

Neuroinflammation is the second major target