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The highest NCDs prevalence from physical inactivity is observed among persons who went on to develop type 2 diabetes, (overall median, 43%), followed by those eventually dying, and those developing colon cancer, coronary heart disease, and breast cancer (overall medians, 43, 43, 42, and 41%, respectively) 3

It provides a critical appraisal into their capacity to modulate immunometabolic reprogramming, emphasizing polyphenols immunomodulatory roles in the maldaptation of organ-specific immune functions as well as their potential use as precise immunonutritional interventions in immunometabolic diseases

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Muoio D.M., Noland R.C., Kovalik J.-P., Seiler S.E., Davies M.N., DeBalsi K.L., Ilkayeva O.R., Stevens R.D., Kheterpal I., Zhang J., et al