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Description
Notably, 7 days of MOTS-c treatment significantly improved skeletal muscle insulin sensitivity in young and older C57BL/6J mice also fed a high-fat diet 15

doi: 10.1016/0005-2736(77)90402-3

The authors recommend considering L-carnitine as a potential lipid-modulating agent, either alone or in combination with other lipid-lowering drugs, based on suggestive evidence
Which requires a caloric deficit

Lee EC, Desai U, Gololobov G, Hong S, Feng X, Yu XC, Gay J, Wilganowski N, Gao C, Du LL, Chen J, Hu Y, Zhao S, Kirkpatrick L, Schneider M, Zambrowicz BP, Landes G, Powell DR, Sonnenburg WK (2009) Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL)
