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Description
5-Amino-1MQ is a small molecule that works by inhibiting NNMT (Nicotinamide N-methyltransferase), an enzyme that reduces NAD levels in the body

Key gap: no human trial has been published, and no human pharmacokinetic study is widely available
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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Beydoun M.A., Gamaldo A.A., Canas J.A., Beydoun H.A., Shah M.T., McNeely J.M., Zonderman A.B

Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration