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Description
In the TME, macrophages can manifest as the M1 type (characterized by inflammatory and antitumour responses) or M2 type (involved in the repair of damaged tissues and anti-inflammation), but the TME tends to induce the differentiation of macrophages towards the M2 type (120122)
Townsend et al., 2003
[DOI] [PubMed] [Google Scholar] [205].Reddy PH

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The framingham heart study: a pivotal legacy of the last millennium