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Alcoholic liver disease is the second major worldwide contributor to cirrhosis incidence, accounting for almost one-third of cases (NIDDK 2014a)

Min M, Nadora D, Chakkalakal M, et al

So I couldn't imagine not using it

Biochemically, LCD proceeds upon LMP when cells are exposed to various lysosomotropic detergents (e.g., lipid metabolites (phosphatidic acid, sphingosine), ROS), including cathepsins [178,179,180,181] (Fig