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Caution is warranted because animal findings do not reliably map onto what happens in people
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Plasma and urinary metabolomic analysis of gout and asymptomatic hyperuricemia and profiling of potential biomarkers: a pilot study
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The maximal tumor size permitted by the ethics committee was not exceed 10% baseline body weight (at the start of the study) in therapeutic studies, and none of the tumors in this study exceeded this size limit
