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The strength of evidence was evaluated using standardized GRADE criteria, considering factors such as study design, sample size, risk of bias, and the reproducibility of results (see Table 2)

These include nasal inhalation delivery for non-invasive brain therapy for rescue therapy of acute migraine attacks, rescue therapy for heroin and opioid overdose, and neurodegenerative diseases such as Alzheimers

SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: implications for cell survival after irradiation

Barha CK, Galea LA, Nagamatsu LS et al (2017) Personalising exercise recommendations for brain health: considerations and future directions

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