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Biologics The exact causes of injection site reactions due to biologics A 2023 review of 158 studies found that injection site reactions occur in Out of the 16 medications in the review, the one responsible for the most injection site reactions was canakinumab, while secukinumab had the least

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doi: 10.1097/00019442-200111000-00015

These studies did not include lipotropic injections as part of the intervention protocols, and participants were typically excluded if using investigational weight loss compounds
