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PMID: 16352683

AOD-9604 is the better-evidenced of the two

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The Key Factors in the Methylation Cycle We will now consider three important causes of interruption to the methylation cycle: Vitamin B12 deficiency Folate deficiency MTHFR mutation Vitamin B12 deficiency If vitamin B12 is deficient, the methyl group cannot be transferred from methylfolate to the methionine cycle

and the proportion of 30-day periods of care with and without any therapy visits, nursing visits, and/or aide/social worker visits