l-glutathione liver cancer Application of glutathione depletion in therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy New insights into T cell

doi: 10.1016/0006-2952(85)90131-5

Funding Statement This work was financially supported by the National Natural Science Foundation of China (32472358), Guangdong Basic and Applied Basic Research Foundation (No

H 2 O 2 can react with ferrous ions in a reaction known as the Fenton reaction to generate the short-lived hydroxyl radicals, which are highly toxic and can cause irreversible damage to essentially all types of cellular macromolecules, including nucleic acids (e.g., mutations), lipids (e.g., oxidized lipids such as 4-HNE), and proteins (e.g., protein carbonylation) [3,4,5]

doi: 10.1152/ajpendo.2001.280.3.E391

Toll-like receptor 7 regulates osteoclastogenesis in rheumatoid arthritis