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However, neither combination prevented atopic sensitization (positive skin prick tests), indicating that probiotics may primarily affect clinical manifestations rather than underlying allergic tendency

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Clinical Practice Guideline: Irritable bowel syndrome with constipation and functional constipation in the adult

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In addition, melatonin treatment reduced mitochondrial swelling, ROS production, and cytoplasmic cytochrome c release and increased mitochondrial antioxidant enzyme activity, adenosine triphosphate production, and mitochondrial membrane potential