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Description
Finnish Acromegaly Study G, Pukkala E

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

10.1038/nature10954 [DOI] [PMC free article] [PubMed] [Google Scholar] Mann A., Illing S., Miess E., Schulz S

Chem Papers

Similarly, antioxidant supplementation with vitamin E (vit E) or selenium (Se) enhances oxidative stability in animal tissues, extending shelf life while preserving nutritional value [7, 8]
