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Calcott MJ, Ackerley DF (2014) Genetic manipulation of non-ribosomal peptide synthetases to generate novel bioactive peptide products

For most seniors, liposomal or sublingual forms offer the best balance of effectiveness and convenience

Although N-methylation modification at the glycine position (Analogue 1.65 ) did not show a decrease in degradation in the presence of GGT, the N-methylation of the cysteine or glutamic acid were able to substantially decrease degradation nine-fold

1986, 250: G236-G243

May 1989;92(5):694-702
