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The deficiency or mutation of Kelch-like ECH-associated protein 1 (KEAP1), mediated by p62, leads to the activation and upregulation of Nrf2

The addition of IMiDs for patients with daratumumab-refractory multiple myeloma can overcome refractoriness to both agents

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2.12 BALB/c mice in Alzheimers disease research BALB/c mice have emerged as a valuable model in AD research due to their TH2-biased immune responses and genetically stable background

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