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PINK1 and Parkin interact to mediate mitophagy, thereby maintaining mitochondrial homeostasis

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15 Sublingual B12 is also much more affordable than injections, and avoids the pain and cost of repeated clinic visits

In contrast, an increased dependence on mitochondrial ATP and an increased capacity of FAO and amino acid oxidation (AAO) were recorded in noncontrollers (Figure 3J), which is in line with the increased expression of CPT1a and MCAD

As one review paper notes, even the governmental agencies responsible for defining dietary recommendations acknowledge that the benefits of micronutrient consumption may continue on a continuum well above the RDA