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Description
Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione

It is the measurement that determines whether the ferroptosis mechanism is correctly assigned or attributed to the wrong metabolite

Calculating the GSH/GSSG ratio from these measurements provides a reliable indicator of intracellular redox status in preclinical models

Glutathione is a naturally occurring antioxidant produced inside the body and found in nearly every cell

L., & Wilson, D
