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Description
Large amounts of ROS activate NF-B, TGF-1, AMPK, and other pathways, which induce renal inflammation, autophagy, and fibrosis, triggering abnormal kidney structure and function

The development of highly selective or isoform-specific inhibitors will reduce side effects and is an important goal for the near future

Cervenka, I., Agudelo, L

As for how much to take, thats more a personal diet calculus

Endocr Dev
