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Enzymatic reactions, such as those involving cytochrome P450, xanthine oxidase, and nitric oxide synthase, can also produce free radicals [14]
However, there may be minor side effects like bruising at the injection site or dizziness

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doi: 10.3390/nu15061496 104 MargolisK
Notably, increased NAD+ levels also activate NAD+dependent signaling pathways such as sirtuins (SIRT1/SIRT3), further enhancing mitochondrial biogenesis and energy metabolism