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However, research shows that people with low B12 tend to have higher BMI, reduced physical activity, disrupted fat cell gene expression, and elevated homocysteine, all of which can contribute to gradual weight gain over time

Eur J Med Res 28, 425 (2023)

Caffeine "Heart palpitations are a potential concern with supplements containing green tea, guarana, yerba mate, or kola nut all ingredients that naturally contain caffeine," says Tod Cooperman, MD, the president of ConsumerLab, an independent testing company in White Plains, New York, focused on health and nutrition products

Thiamine, selenium, zinc, and magnesium are safe and helpful for most people with Hashimotos, and most people will see a significant benefit from these supplements

The effect typically persists while you are taking the medication and may continue for a day or two after stopping it