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While mice lacking PINK1 or Parkin do not exhibit significant PD-related phenotypes, a study has demonstrated that these mice accumulate mtDNA mutations, which consequently promotes inflammation in aged Parkin/ (also termed 'Mutator') mice

Protective effects of infliximab on lung injury induced by methotrexate
doi: 10.1111/j.1440-1746.2005.03832.x

Minich, A Review of the Science of Colorful, Plant-Based Food and Practical Strategies for Eating the Rainbow, Journal of Nutrition and Metabolism, vol

Little of the TSS pathway in antioxidant capacity in sickle cell disease (SCD) is known
