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Journal of Clinical Investigation, 70(4), 889898
Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells

Alternatively, the loss of extramitochondrial Fe-S protein stability may be a consequence of Fe-S cluster oxidation due to cytosolic ROS accumulation 56,80

Following treatment, media was replaced with 80% (v/v) methanol (cooled to 80C) containing 500 nmol 6-chloronicotinamide (6-CN) as an internal standard (IS) to extract cellular metabolites

Koenen, T
