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Without supplementation or fortified foods, deficiency is almost inevitable over time

N., Israelian, A

C., Hughes, I

Total weight loss at 48-68 weeks on the combination is difficult to predict without clinical trial data, but based on individual compound data (retatrutide at 24-28.7% and the additive benefit seen with CagriSema), a reasonable estimate for the combination is 25-35% total body weight reduction in high responders
mPFS 4.4 months vs 2.9 months) (68)
