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glutathione and bone marrow transplant High-glutathione mesenchymal stem cells isolated using the FreSHtracer probe enhance cartilage regeneration in a rabbit chondral defect model | Biomaterials Research What Is the Bone Marrow
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For protein or enzyme replacement therapy in monogenic disorders, the major risk factor for immunogenicity is the absence of residual (functional or non-functional) cross-reactive immunological material (CRIM), which could result in the complete lack of production of native protein, translating to a lack of tolerance to replacement therapy

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