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Heberling CA, Dhurjati PS, Sasser M (2013) Hypothesis for a systems connectivity model of autism spectrum disorder pathogenesis: links to gut bacteria, oxidative stress, and intestinal permeability
this was facilitated by the induction of the expression of heme oxygenase (HO-1) and inhibition of NF-kB, p38 MAPK, and JNK
High GGT levels often indicate vitamin B6, B9, or B12 deficiencies, reduced antioxidant activity, and increased reactive oxygen species (ROS)
Progressive disease stages shorten the half-life of L-Dopa and narrow its therapeutic window
Credit: Patrick Mansell / Penn State
