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Since IC is a chronic condition, therapy and monitoring should be carried out over the long term [19]
Differential effects of cocaine access and withdrawal on glutamate type 1 transporter expression in rat nucleus accumbens core and shell

The denervation supersensitivity may be due to decreased reuptake of excitatory neurotransmitters, upregulation of receptors on the postsynaptic membrane, or alteration of degradation and synthesis of receptors

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