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In a renal ischemiareperfusion model, Dex (25 gkg 1 , i.p.) amplified SIRT3 activity, curtailed the release of cytochrome c (Cyt C), and reduced CypD (Cyclophilin D) acetylation and mitochondrial apoptosis, providing renoprotection [51]

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To view a copy of this licence, visit About this article Cite this article Takeuchi, A., Oda, N., Takada, K

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These results provide backing up for the safety of AST for future clinical studies