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as a result, most controlled efficacy studies referenced to date use parenteral dosing with defined schedules to sustain ERR activation

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

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one or more nucleotides of the oligonucleotide are linked by non-standard linkages or backbones (e.g., modified internucleoside linkages or modified backbones)